ارزیابی وضعیت خلقی کارگران در معرض مواجهه با مخلوط حلال ها ی آلی (مطالعه موردی: یک صنعت رنگ)

Introduction: Exposure to organic solvents cause adverse effects on various systems such as the central nervous system, behavioral and cognitive changes, sleep disorders, as well as changes in mood. This study was aimed to evaluate the effect of long term exposure to mixed organic solvents on positive and negative aspects of the mood of the workers of a painting industry.   Material and Methods: In this cross-sectional study, based on the obtained results of Gas chromatography–mass spectrometry (GC-MS) analysis and neuro-behavioral effects of benzene, toluene, ethylbenzene and xylene (BTEX) compounds, these compounds were selected as the main organic solvents for the study and the amount of these compounds was quantitatively determined according to the National Institute for Occupational Safety and Health (NIOSH) 1501. Furthermore, the mood status of workers was evaluated by the validated Persian version of BRUMS (The Brunel Mood Scale) questionnaire and the obtained data were analyzed using SPSS software, version 24. Results: The mean of exposure to mixed organic solvents in different sections of the exposed group was reported to be 0, 0.27, 0.76, and 2.6 ppm. By increasing exposure to mixed organic solvents from the first quartile to the fourth quartile, fatigue and calmness scores were increased with a strong correlation (r = 0.7). Also the fatigue and calmness scores in the groups having elevated exposure were significantly higher than the control group. Furthermore, the obtained scores for tension, depression and anger in the exposed group were significantly higher than control group (p- value <0.05). There was no significant relationship between demographic data such as age, work experience and smoking with different subscale of mood status. Conclusion: Long term exposure to low level of BTEX compounds has made an adverse effect on positive and negative mood status in different aspects. Also, increasing the level of exposure to mixed organic solvents was positively correlated to the obtained scores for fatigue and calmness.